Even something as ubiquitous as JSON is not handled in the same way in different databases, same goes for Dates, and UUID. I am not even mentioning migrations scripts. As soon as you start writing raw SQL, I pretty sure you will hit a compatibility issue.
I was specifically talking about python, can’t argue with golang. OK you have a valid point for performance, gotta keep an eye on that. However, I am satisfied for our CRUD api
You don’t even mention the 2 main advantages:
React +python + postgres/sqlite