A shortage of diabetes drug Ozempic that is used off-label for weight loss is expected in Canada, the manufacturer says.

By Nicole Ireland / The Canadian Press

Then why isn’t production increased?

It’s not like the hype is new, manufacturers just didn’t keep up. Whether stupidity or intent, I don’t know.

You are correct that it’s the drug company at fault here too, not just the public. It’s also the fault of doctors that are continuing to prescribe it off-label for weight loss.

Why are the doctors at fault? There’s a drug that helps patients achieve their weight loss goals. As long as it’s prescribed to overweight people, that’s perfectly fine.

Because not every doctor tells their patients the risks, including that you must continue taking it or risk gaining more weight back if you stop. It’s making more people overweight in the long run because they stop due to serious headaches (the most common side-effect).

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Most health care providers go over risks and benefits prior to initiating any kind of treatment. What the hell are you on about?

If I have an overweight patient who has tried for years to lose weight but can’t sustain it (which is the case for most overweight people) and are at risk for metabolic diseases and cardiovascular complications, and I have something that evidence tells me can help with weight management, you bet your ass I’m going to talk about it as an option.

Or would you prefer that fat people remain fat until they develop diabetes (and its various associated complications) before I’m even allowed to discuss semaglutide?

Patients are oftentimes aware of the potential side effects and the rebound weight gain. People don’t jump straight to an expensive injectable drug as the first option for weight management. It’s something that they try after a string of failed attempts by other means.

Most health care providers go over risks and benefits prior to initiating any kind of treatment.

Sure, most do. I’m talking about those that do not.

and are at risk for metabolic diseases and cardiovascular complications

Seems pretty close the intended use in this case? Not sure this would qualify as the off-label use I’m talking about.

Or would you prefer that fat people remain fat until they develop diabetes (and its various associated complications) before I’m even allowed to discuss semaglutide?

When did I say that? I said nothing of the sort. I’m specifically talking about those that aren’t even overweight using it, or those without risk factors for diabetes. Because that’s happening, and it’s happening a lot.

People don’t jump straight to an expensive injectable drug as the first option for weight management.

This is not true for everyone. Many see Ozempic as a “magic bullet” for weight loss when that is not what it is.

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I don’t see many providers in my life that prescribe semaglutide to non-diabetic people who aren’t considered overweight. Social media isn’t real life. Most providers won’t prescribe medications for weight loss unless the BMI supports it. The fact of the matter is that A LOT of people in Canada and US are overweight and with that comes with a slew of health complications that frankly I’d like to mitigate for my patients.

fwiw my cardiologist suggested i get my GP to prescribe it. I’m going to pass tho as I’m not diabetic.

You don’t know that. That’s simply pulling “facts” out of your ass.

It’s way too little time on the market to judge the long term effects.

Of course it’s early, but Ozempic rebound is a real thing that you can easily search to study. Here’s an example for you: https://www.cnbc.com/2023/03/29/people-taking-obesity-drugs-ozempic-and-wegovy-gain-weight-once-they-stop-medication.html

Maybe you were the one pulling “facts out of your ass”?

Just like with any other diet. That’s null news.

The drug company knows exactly what it’s doing here - I came out Barbie the other day and there’s a fucking Ozempic ad besides the theatre inside the Famous Players.

The drug was only approved last December. Everyone needs a bit more patience.

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