quick google search implies that FL Studio “works flawlessly” on linux through wine (which you also use for video games) 5 years ago already. https://jstaf.github.io/posts/flstudio-on-linux/
I haven’t had a single game that needed editing ini files in ~ a year of gaming on linux. Most of the time it works straight from Steam as you’d expect on Windows. If not it’s usually just checking protondb.com to find out what launch arguments and proton version a steam game needs/works best with.
If a game is not on steam it’s usually easiest to use Lutris to handle the launcher setup as most other launchers like epic and uplay do not run natively on Linux so they need to be launched in the same container as windows games which Lutris fully takes care of.
Note that some games have kernel level anti cheat which will never work on linux. (eg valorant)
I’m using rocm with ollama and it works out of the box on 6900XT